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Journal article

Physical mapping of the human T-cell receptor beta gene complex, using yeast artificial chromosomes.

Abstract:

Yeast artificial chromosomes (YACs) were used to construct a physical map of the germline human T-cell beta chain gene complex (TCRB). Variable region genes (BV) for the 25 known subfamilies were used as probes to screen the ICRF AM4x YAC library. Of the five positive YACs identified, one YAC designated B3, 820 kilobase pairs (kbp) in size, scored positive for all 25 TCRBV subfamilies plus the constant region genes (BC) when analyzed by pulse field gel electrophoresis. Restriction enzyme mapp...

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Publication status:
Published

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Publisher copy:
10.1007/bf00163990

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Publisher:
Springer-Verlag
Journal:
Immunogenetics More from this journal
Volume:
41
Issue:
6
Pages:
337-342
Publication date:
1995-01-01
DOI:
EISSN:
1432-1211
ISSN:
0093-7711
Language:
English
Keywords:
Pubs id:
pubs:35691
UUID:
uuid:62bb4be3-3616-44d9-a840-aafe3a5404c7
Local pid:
pubs:35691
Source identifiers:
35691
Deposit date:
2012-12-19

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