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Genomic analyses of the Chlamydia trachomatis core genome show an association between chromosomal genome, plasmid type and disease

Abstract:
Background Chlamydia trachomatis (Ct) plasmid has been shown to encode genes essential for infection. We evaluated the population structure of Ct using whole-genome sequence data (WGS). In particular, the relationship between the Ct genome, plasmid and disease was investigated. Results WGS data from 157 Ct isolates deposited in the Chlamydiales pubMLST database (http://pubMLST.org/chlamydiales/) were annotated with 902 genes including the core and accessory ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12864-018-4522-3

Authors


Versteeg, B More by this author
Bruisten, SM More by this author
Pannekoek, Y More by this author
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Zoology
Oxford college:
Hertford College
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Funding agency for:
Jolley, KA
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Funding agency for:
Maiden, MCJ
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Funding agency for:
Maiden, MCJ
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Funding agency for:
Harrison, OB
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Funding agency for:
Harrison, OB
Publisher:
BioMed Central Publisher's website
Journal:
BMC Genomics Journal website
Volume:
19
Pages:
Article: 130
Publication date:
2018-02-09
Acceptance date:
2018-01-31
DOI:
ISSN:
1471-2164
Pubs id:
pubs:824697
URN:
uri:62ac85fc-4456-4086-a620-e0a15c8bef3c
UUID:
uuid:62ac85fc-4456-4086-a620-e0a15c8bef3c
Local pid:
pubs:824697

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