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Journal article

Dose-finding study of the novel tuberculosis vaccine, MVA85A, in healthy BCG-vaccinated infants.

Abstract:

BACKGROUND: BCG, the only licensed tuberculosis vaccine, affords poor protection against lung tuberculosis in infants and children. A new tuberculosis vaccine, which may enhance the BCG-induced immune response, is urgently needed. We assessed the safety of and characterized the T cell response induced by 3 doses of the candidate vaccine, MVA85A, in BCG-vaccinated infants from a setting where tuberculosis is endemic. METHODS:  Infants aged 5-12 months were vaccinated intradermally with either ...

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Publication status:
Published

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Publisher copy:
10.1093/infdis/jir195

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Journal:
Journal of infectious diseases More from this journal
Volume:
203
Issue:
12
Pages:
1832-1843
Publication date:
2011-06-01
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Language:
English
Keywords:
Pubs id:
pubs:151322
UUID:
uuid:62a4c637-dd1b-4601-a4ff-1e4e088fac88
Local pid:
pubs:151322
Source identifiers:
151322
Deposit date:
2012-12-19

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