Imaging attentional modulation of pain in the periaqueductal gray in humans.

Journal article

Pain is an unpleasant sensory and emotional experience usually triggered by stimulation of peripheral nerves and often associated with actual or potential tissue damage. It is well known that pain perception for patients and normal subjects can be modulated by psychological factors, such as attention, stress, and arousal. Our understanding of how this modulation occurs at a neuroanatomical level is poor. Here we neuroanatomically defined a key area in the network of brain regions active in re...

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Authors: Tracey, I; Ploghaus, A; Gati, J; Clare, S; Smith, S

• Publication status: Published
• Journal: Journal of neuroscience : the official journal of the Society for Neuroscience
• Volume: 22
• Issue: 7
• Pages: 2748-2752
• Publication date: 2002-04-01
• EISSN: 1529-2401
• ISSN: 0270-6474
• Language: English
• Keywords: Male; Neural Pathways; Physical Stimulation; Female; Echo-Planar Imaging; Behavior; Pain; Hot Temperature; Hand; Pain Measurement; Attention; Periaqueductal Gray; Pain Threshold; Magnetic Resonance Imaging; Humans; Adult