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Associations Between Restrictive Fluid Management and Renal Function and Tissue Perfusion in Adults With Severe Falciparum Malaria: A Prospective Observational Study

Abstract:

Background: Liberal fluid resuscitation has proved harmful in adults with severe malaria, but the level of restriction has not been defined.
Methods: In a prospective observational study in adults with severe falciparum malaria, restrictive fluid management was provided at the discretion of the treating physician. The relationships between the volume of fluid and changes in renal function or tissue perfusion were evaluated.
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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/infdis/jiz449

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
Green Templeton College
Role:
Author
ORCID:
0000-0002-3596-3267
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Expand authors...
More from this funder
Grant:
106698/Z/14/A milestone
More from this funder
Grant:
106698/B/14/Z milestone
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Infectious Diseases Journal website
Volume:
221
Issue:
2
Pages:
285-292
Place of publication:
United States
Publication date:
2019-08-31
Acceptance date:
2019-08-30
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Pmid:
31504666
Language:
English
Keywords:
Pubs id:
1054158
Local pid:
pubs:1054158
Deposit date:
2020-04-06

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