Journal article
IgG-specific cell-based assay detects potentially pathogenic MuSK-Abs in seronegative MG
- Abstract:
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To increase the detection of MuSK-Abs using a CBA and test their pathogenicity.Sera from 69 MuSK-RIA-positive patients with myasthenia gravis (MG) (Definite MuSK-MG), 169 patients negative for MuSK-RIA and AChR-RIA (seronegative MG, SNMG), 35 healthy individuals (healthy controls, HCs), and 16 NMDA receptor-Ab-positive (NMDAR-Ab) disease controls were tested for binding to MuSK on a CBA using different secondary antibodies.Initially, in addition to 18% of SNMG sera, 11% of HC and 19% of NMDAR...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 626.6KB)
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- Publisher copy:
- 10.1212/nxi.0000000000000357
Authors
Funding
Bibliographic Details
- Publisher:
- Lippincott, Williams & Wilkins Publisher's website
- Journal:
- Neurology, Neuroimmunology & Neuroinflammation Journal website
- Volume:
- 4
- Issue:
- 2
- Pages:
- 1-9
- Publication date:
- 2017-06-05
- Acceptance date:
- 2017-04-06
- DOI:
- EISSN:
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2332-7812
- Pmid:
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28626780
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:702310
- UUID:
-
uuid:6263547a-1e0b-48d2-adae-a063e2b3e02b
- Local pid:
- pubs:702310
- Source identifiers:
-
702310
- Deposit date:
- 2018-01-10
Terms of use
- Copyright holder:
- © 2017 Huda, et al
- Copyright date:
- 2017
- Notes:
- This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
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