Tissue capillary supply--it's quality not quantity that counts!

Journal article

This article explores how common misunderstandings about the microcirculation - that capillary supply varies directly with O(2) demand, that local capillary supply in muscle is determined by fibre type and that it is appropriate to model capillary distribution as either random or in a fixed geometric pattern - arise from quantifying capillarity by simple measures of quantitative extent, rather than the more functionally relevant qualitative distribution. We show that the latter approach revea...

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Authors: Egginton, S; Gaffney, E

• Journal: Experimental physiology
• Volume: 95
• Issue: 10
• Pages: 971-979
• Publication date: 2010-10-01
• DOI: 10.1113/expphysiol.2010.053421
• EISSN: 1469-445X
• ISSN: 0958-0670
• Language: English
• Keywords: Capillaries; Biological Transport; Muscle, Skeletal; Animals; Regional Blood Flow; Neovascularization, Physiologic; Oxygen Consumption; Models, Cardiovascular; Humans; Computer Simulation; Microcirculation; Oxygen