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Optimum population-level use of artemisinin combination therapies: a modelling study.

Abstract:

Artemisinin combination therapies (ACTs) are used worldwide as first-line treatment against confirmed or suspected Plasmodium falciparum malaria. Despite the success of ACTs at reducing the global burden of malaria, emerging resistance to artemisinin threatens these gains. Countering onset of resistance might need deliberate tactics aimed at slowing the reduction in ACT effectiveness. We assessed optimum use of ACTs at the population level, specifically focusing on a strategy of multiple firs...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/s2214-109x(15)00162-x

Authors


Nguyen, TD More by this author
Olliaro, P More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine, Thailand/Laos MOP
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Tropical Medicine, Vietnam MOP
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Publisher:
Elsevier Publisher's website
Journal:
The Lancet. Global health Journal website
Volume:
3
Issue:
12
Pages:
e758-e766
Publication date:
2015-12-05
DOI:
EISSN:
2214-109X
ISSN:
2214-109X
URN:
uuid:623d6c90-e86b-49d1-826a-5481502e1d48
Source identifiers:
579426
Local pid:
pubs:579426
Language:
English

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