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Journal article

Interleukin-4 promotes human CD8 T cell expression of CCR7.

Abstract:

Despite strong evidence supporting a pathway of human T cell differentiation characterized by changes in the expression of CCR7, CD28, CD27 and CD62L, few studies have addressed the mechanisms of pathway regulation. Cutaneous lymphocyte-associated antigen (CLA)-positive skin-homing CD8(+) T cells expressed significantly elevated levels of activation markers compared with CLA(-) CD8(+) T cells in individuals (n = 27) with cutaneous atopic disease. Despite such an activated phenotype, CLA(+) T ...

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Publication status:
Published

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Authors


Seneviratne, SL More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
di Gleria, K More by this author
Bailey, AS More by this author
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Journal:
Immunology
Volume:
120
Issue:
1
Pages:
66-72
Publication date:
2007-01-05
DOI:
EISSN:
1365-2567
ISSN:
0019-2805
URN:
uuid:6238bfd7-921a-4fd6-81b5-a657582e567a
Source identifiers:
17503
Local pid:
pubs:17503

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