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Normothermic machine perfusion (NMP) inhibits proinflammatory responses in the liver and promotes regeneration

Abstract:
Background and Aims Liver transplantation is a successful treatment for patients with liver failure. However, organ shortage results in over 11% of patients losing their chance of a transplant due to liver decompensation and death. Ischemia/reperfusion injury (IRI) following conventional cold storage (CS) is a major cause of injury leading to graft loss after liver transplantation. A novel method of organ preservation, normothermic machine perfusion (NMP), provides oxygen and... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1002/hep.30475

Authors


Xystrakis, E More by this author
Ghnewa, YG More by this author
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Publisher:
Wiley Publisher's website
Journal:
Hepatology Journal website
Volume:
70
Issue:
2
Pages:
682-695
Publication date:
2018-12-18
Acceptance date:
2018-10-02
DOI:
EISSN:
1527-3350
ISSN:
0270-9139
Pubs id:
pubs:953325
URN:
uri:621a5534-afdb-4d47-8951-2782894efebe
UUID:
uuid:621a5534-afdb-4d47-8951-2782894efebe
Local pid:
pubs:953325

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