AFM and QCM-D studies in liquid of fibrinogen and vitronectin on Ti and Ta surfaces

Journal article

The adsorption of fibrinogen followed by specific fibrinogen anti-fibrinogen reaction from a tris-buffered solution at 37°C onto Au, Ta and Ti surfaces was investigated. The concentrations of fibrinogen used were 1 mg/ml, which were close to that found in blood and 0.03 mg/ml. It was found that very small amount of silver on the gold surface have a large effect on the amount of fibrinogen adsorbed. Globular monomeric and polymeric vitronectin proteins for low concentrations were identified using atomic force microscopy (AFM) in liquid.

Authors: Hemmersam, A; Contera, SA; Foss, M; Jensen, J; Andreasen, P

• Journal: Transactions - 7th World Biomaterials Congress
• Pages: 788-788
• Publication date: 2004-01-01
• Language: English