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Journal article

Parkinsonian beta oscillations in the external globus pallidus and their relationship with subthalamic nucleus activity.

Abstract:

Inappropriately synchronized beta (beta) oscillations (15-30 Hz) in the subthalamic nucleus (STN) accompany movement difficulties in idiopathic Parkinson's disease (PD). The cellular and network substrates underlying these exaggerated beta oscillations are unknown but activity in the external globus pallidus (GP), which forms a candidate pacemaker network with STN, might be of particular importance. Using a clinically relevant rat model of PD, we demonstrate that oscillatory activity in GP ne...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
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Journal:
Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
28
Issue:
52
Pages:
14245-14258
Publication date:
2008-12-01
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Source identifiers:
70900
Language:
English
Keywords:
Pubs id:
pubs:70900
UUID:
uuid:62155055-b949-4889-b654-431da7bc4956
Local pid:
pubs:70900
Deposit date:
2012-12-19

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