Journal article
Biowire model of interstitial and focal cardiac fibrosis
- Abstract:
-
Myocardial fibrosis is a severe global health problem due to its prevalence in all forms of cardiac diseases and direct role in causing heart failure. The discovery of efficient antifibrotic compounds has been hampered due to the lack of a physiologically relevant disease model. Herein, we present a disease model of human myocardial fibrosis and use it to establish a compound screening system. In the Biowire II platform, cardiac tissues are suspended between a pair of poly(octamethylene malea...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- American Chemical Society Publisher's website
- Journal:
- ACS Central Science Journal website
- Volume:
- 5
- Issue:
- 7
- Pages:
- 1146-1158
- Publication date:
- 2019-06-04
- DOI:
- EISSN:
-
2374-7951
- ISSN:
-
2374-7943
Item Description
- Keywords:
- Pubs id:
-
pubs:1022804
- UUID:
-
uuid:620c76e0-0304-4869-93ab-08423e388dea
- Local pid:
- pubs:1022804
- Source identifiers:
-
1022804
- Deposit date:
- 2019-07-01
Terms of use
- Copyright holder:
- American Chemical Society
- Copyright date:
- 2019
- Notes:
- © 2019 American Chemical Society. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
- Licence:
- Other
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