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Relationship of neurofibrillary pathology to cerebral amyloid angiopathy in Alzheimer's disease.

Abstract:

Over 90% of patients with Alzheimer's disease (AD) develop cerebral amyloid angiopathy (CAA). Severe dyshoric CAA, in which amyloid extends into the surrounding brain parenchyma, may be associated with adjacent clustering of tau-immunopositive neurites but the relationship of CAA to neurofibrillary pathology has not been systematically investigated. In the present study this relationship was examined in sections of frontal, temporal and parietal cortex from 25 AD patients with moderate to sev...

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Publication status:
Published

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Authors


Williams, S More by this author
Chalmers, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Journal:
Neuropathology and applied neurobiology
Volume:
31
Issue:
4
Pages:
414-421
Publication date:
2005-08-05
DOI:
EISSN:
1365-2990
ISSN:
0305-1846
URN:
uuid:6205b4d2-968d-4c85-97ae-780452228f41
Source identifiers:
33163
Local pid:
pubs:33163

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