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Measurement of refractive index by nanoparticle tracking analysis reveals heterogeneity in extracellular vesicles.

Abstract:

INTRODUCTION: Optical techniques are routinely used to size and count extracellular vesicles (EV). For comparison of data from different methods and laboratories, suitable calibrators are essential. A suitable calibrator must have a refractive index (RI) as close to that of EV as possible but the RI of EV is currently unknown. To measure EV, RI requires accurate knowledge of size and light scattering. These are difficult to measure as most EVs cannot be resolved by light microscopy and their ...

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Publisher copy:
10.3402/jev.v3.25361

Authors


Gardiner, C More by this author
Tannetta, D More by this author
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Journal:
Journal of extracellular vesicles
Volume:
3
Pages:
25361
Publication date:
2014
DOI:
EISSN:
2001-3078
URN:
uuid:6204238c-f65f-4496-a550-1592adf662b8
Source identifiers:
491809
Local pid:
pubs:491809

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