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Investigation of candidate risk genes for neuropsychiatric disease in vitro and in vivo using ENU mutagenesis

Abstract:

Schizophrenia is a complex mental disorder characterised by positive symptoms such as hallucinations and psychosis, negative symptoms such as avolition and anhedonia, and cognitive defects. Schizophrenia risk has a genetic component, and it is likely that this is caused by interaction between numerous genes with individually small effects. Environment also plays a role; factors associated with schizophrenia include drug use, prenatal stressors and living environment.

Candidate genes...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Department:
Physiology and Anatomy
Role:
Author

Contributors

Department:
MRC Harwell Institute
Role:
Supervisor
Role:
Supervisor
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:6204220c-3680-4549-8399-872c6dd4b473
Deposit date:
2017-04-05

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