Journal article icon

Journal article

Determining the most appropriate components for a composite clinical trial outcome.

Abstract:

BACKGROUND: Because composite end points augment event rates, they are often thought to increase statistical power. This may not be true if the intervention has a lesser effect on some components of the composite. Consequently, treatment effect size may depend on the choice of composite. METHODS: To explore this issue, we performed a meta-analysis to determine the effect of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers on individual cardiovascular (CV) outcomes. W...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.ahj.2008.05.018

Authors


Expand authors...
Journal:
American heart journal
Volume:
156
Issue:
4
Pages:
633-640
Publication date:
2008-10-01
DOI:
EISSN:
1097-6744
ISSN:
0002-8703
Source identifiers:
244758

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP