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Journal article

Autocrine regulation of insulin secretion.

Abstract:

Impaired insulin secretion from pancreatic β-cells is a major factor in the pathogenesis of type 2 diabetes. The main regulator of insulin secretion is the plasma glucose concentration. Insulin secretion is modified by other nutrients, circulating hormones and the autonomic nervous system, as well as local paracrine and autocrine signals. Autocrine signalling involves diffusible molecules that bind to receptors on the same cell from which they have been released. The first transmitter to be i...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Diabetes, obesity and metabolism
Volume:
14 Suppl 3
Issue:
SUPPL.3
Pages:
143-151
Publication date:
2012-10-01
DOI:
EISSN:
1463-1326
ISSN:
1462-8902
Source identifiers:
350473
Language:
English
Keywords:
Pubs id:
pubs:350473
UUID:
uuid:61f196f1-0354-4493-b422-eec3ad49cdf3
Local pid:
pubs:350473
Deposit date:
2013-11-17

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