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A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action

Abstract:

International sustainable development goals for the elimination of viral hepatitis as a public health problem by 2030 highlight the pressing need to optimize strategies for prevention, diagnosis and treatment. Selected or transmitted resistance associated mutations (RAMs) and vaccine escape mutations (VEMs) in hepatitis B virus (HBV) may reduce the success of existing treatment and prevention strategies. These issues are particularly pertinent for many settings in Africa where there is high H...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pntd.0006629

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
ORCID:
0000-0001-8398-0689
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Subgroup:
NDM Experimental Medicine
More by this author
Institution:
University of Oxford
Division:
University Administration and Services
Department:
Academic Resources & Information Systems
Subgroup:
IT Services
Oxford college:
St Peters College
ORCID:
0000-0002-3039-6849
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ORCID:
0000-0001-5639-0528
Geretti, A-M More by this author
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Funding agency for:
Mokaya, J
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Funding agency for:
Matthews, PC
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS Neglected Tropical Diseases Journal website
Volume:
12
Issue:
8
Pages:
e0006629
Publication date:
2018-08-06
Acceptance date:
2018-06-22
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Pubs id:
pubs:935399
URN:
uri:61e644b1-d671-4886-832e-8af0f23d86b7
UUID:
uuid:61e644b1-d671-4886-832e-8af0f23d86b7
Local pid:
pubs:935399
Language:
English
Keywords:

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