- Abstract:
-
Human postmortem brain studies are critical for elucidating the pathophysiology and etiology of schizophrenia and other major mental illnesses. The traditional approach compares patients and control subjects but is potentially confounded by a number of artifacts, including medication, substance misuse, and other secondary effects of illness. Genetic advances now make possible a novel approach that focuses on how allelic variation in risk-associated genes affects expression and function of tra...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.biopsych.2010.10.032
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- Journal:
- Biological psychiatry
- Volume:
- 69
- Issue:
- 2
- Pages:
- 140-145
- Publication date:
- 2011-01-05
- DOI:
- EISSN:
-
1873-2402
- ISSN:
-
0006-3223
- URN:
-
uuid:61d44ef6-7c3a-4252-a9da-fdb305d93834
- Source identifiers:
-
110390
- Local pid:
- pubs:110390
- Copyright date:
- 2011
Journal article
Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains.
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