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Journal article

Toll-like receptors and macrophage activation in atherosclerosis.

Abstract:

Atherosclerosis is a multi-factorial inflammatory disease and is the primary initiator of coronary artery and cerebrovascular disease. Initially believed to be exclusively lipid-driven, recent evidence demonstrates that inflammation is a significant driving force of the disease. Cellular components of innate immunity, for example monocytes and macrophages, play a predominant role in atherosclerosis. Toll-like receptors (TLRs) are the most characterised innate immune receptors and recent evide...

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Publication status:
Published

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Publisher copy:
10.1016/j.cca.2011.08.021

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Clinica chimica acta; international journal of clinical chemistry More from this journal
Volume:
413
Issue:
1-2
Pages:
3-14
Publication date:
2012-01-01
DOI:
EISSN:
1873-3492
ISSN:
0009-8981
Language:
English
Keywords:
Pubs id:
pubs:226381
UUID:
uuid:61bedd18-d2e7-4108-bb6c-d079ec1a60b0
Local pid:
pubs:226381
Source identifiers:
226381
Deposit date:
2012-12-19

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