- Abstract:
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Rationale: Current cardiovascular clinical imaging techniques offer only limited assessment of innate immune cell driven inflammation, which is a potential therapeutic target in myocardial infarction (MI) and other diseases. Hyperpolarized magnetic resonance (MR) is an emerging imaging technology that generates contrast agents with 10-20,000 fold improvements in MR signal, enabling cardiac metabolite mapping. Objective: To determine whether hyperpolarized MR using [1-13C]pyruvate can assess t...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 5.7MB)
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- Publisher copy:
- 10.1161/circresaha.117.312535
-
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- Funding agency for:
- Choudhury, RP
- Funding agency for:
- Choudhury, RP
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Circulation Research Journal website
- Volume:
- 122
- Issue:
- 8
- Pages:
- 1084-1093
- Publication date:
- 2018-02-12
- Acceptance date:
- 2018-02-12
- DOI:
- EISSN:
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1524-4571
- ISSN:
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0009-7330
- Pubs id:
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pubs:824873
- URN:
-
uri:61b42a41-712d-4fd4-9715-43052467f5ba
- UUID:
-
uuid:61b42a41-712d-4fd4-9715-43052467f5ba
- Local pid:
- pubs:824873
- Language:
- English
- Keywords:
- Copyright holder:
- Lewis et al.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 The Authors.
Circulation Research is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Journal article
Non-invasive immuno-metabolic cardiac inflammation imaging using hyperpolarized magnetic resonance
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+ British Heart Foundation Centre of Research Excellence
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+ British Heart Foundation Oxbridge Centre for Regenerative Medicine
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