Journal article
Non-invasive immuno-metabolic cardiac inflammation imaging using hyperpolarized magnetic resonance
- Abstract:
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Rationale: Current cardiovascular clinical imaging techniques offer only limited assessment of innate immune cell driven inflammation, which is a potential therapeutic target in myocardial infarction (MI) and other diseases. Hyperpolarized magnetic resonance (MR) is an emerging imaging technology that generates contrast agents with 10-20,000 fold improvements in MR signal, enabling cardiac metabolite mapping. Objective: To determine whether hyperpolarized MR using [1-13C]pyruvate can assess t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 5.7MB)
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- Publisher copy:
- 10.1161/circresaha.117.312535
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Authors
Funding
+ British Heart Foundation Centre of Research Excellence
More from this funder
Funding agency for:
Choudhury, R
Grant:
NNF15CC0018486
+ British Heart Foundation Oxbridge Centre for Regenerative Medicine
More from this funder
Funding agency for:
Choudhury, R
Grant:
NNF15CC0018486
+ Tripartite
Immunometabolism Consortium
More from this funder
Funding agency for:
Choudhury, R
Grant:
NNF15CC0018486
+ Novo Nordisk Foundation
More from this funder
Funding agency for:
Choudhury, R
Grant:
NNF15CC0018486
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Bibliographic Details
- Publisher:
- American Heart Association Publisher's website
- Journal:
- Circulation Research Journal website
- Volume:
- 122
- Issue:
- 8
- Pages:
- 1084-1093
- Publication date:
- 2018-02-12
- Acceptance date:
- 2018-02-12
- DOI:
- EISSN:
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1524-4571
- ISSN:
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0009-7330
- Pmid:
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29440071
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:824873
- UUID:
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uuid:61b42a41-712d-4fd4-9715-43052467f5ba
- Local pid:
- pubs:824873
- Deposit date:
- 2018-02-17
Terms of use
- Copyright holder:
- Lewis et al
- Copyright date:
- 2018
- Notes:
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Copyright © 2018 The Authors.
Circulation Research is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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