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An update on primary sclerosing cholangitis.

Abstract:

PURPOSE OF REVIEW: Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by strictures of the biliary tree complicated by cirrhosis and cholangiocarcinoma. It is immune mediated, although the precise aetiology remains unknown. RECENT FINDINGS: The research into aetiology, genetic associations, pathogenesis, epidemiology, diagnosis of cholangiocarcinoma and medical treatments are discussed. SUMMARY: Multiple gene polymorphisms and human leucocyte antigen haplotyp...

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Publication status:
Published

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Journal:
Current opinion in gastroenterology More from this journal
Volume:
24
Issue:
3
Pages:
377-383
Publication date:
2008-05-01
DOI:
EISSN:
1531-7056
ISSN:
0267-1379
Language:
English
Keywords:
Pubs id:
pubs:181869
UUID:
uuid:61b28608-41e4-40ee-b5e3-f4d3b6bcf0e8
Local pid:
pubs:181869
Source identifiers:
181869
Deposit date:
2012-12-19

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