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Expression profiling of colorectal cancer cells reveals inhibition of DNA replication licensing by extracellular calcium.

Abstract:

Colorectal cancer is one of the most common cancers in industrialised societies. Epidemiological studies, animal experiments, and randomized clinical trials have shown that dietary factors can influence all stages of colorectal carcinogenesis, from initiation through promotion to progression. Calcium is one of the factors with a chemoprophylactic effect in colorectal cancer. The aim of this study was to understand the molecular mechanisms of the anti-tumorigenic effects of extracellular calci...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bbamcr.2017.01.017

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Institution:
University of Oxford
Oxford college:
Somerville College
Role:
Author
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Publisher:
Elsevier Publisher's website
Journal:
BBA Molecular Cell Research Journal website
Volume:
1864
Issue:
6
Pages:
987–996
Publication date:
2017-02-01
Acceptance date:
2017-01-28
DOI:
ISSN:
0167-4889
Source identifiers:
687383
Language:
English
Keywords:
Pubs id:
pubs:687383
UUID:
uuid:619383e7-6558-43c2-a5dc-1fa49aa278c0
Local pid:
pubs:687383
Deposit date:
2017-04-02

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