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Genome-wide association study identifies new prostate cancer susceptibility loci

Abstract:

Prostate cancer (PrCa) is the most common non-skin cancer diagnosed among males in developed countries and the second leading cause of cancer mortality, yet little is known regarding its etiology and factors that influence clinical outcome. Genome-wide association studies (GWAS) of PrCa have identified at least 30 distinct loci associated with small differences in risk. We conducted a GWAS in 2782 advanced PrCa cases (Gleason grade ≥ 8 or tumor stage C/D) and 4458 controls with 571 243 single...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddr295

Authors


Journal:
HUMAN MOLECULAR GENETICS More from this journal
Volume:
20
Issue:
19
Pages:
3867-3875
Publication date:
2011-10-01
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
Language:
English
Pubs id:
pubs:177367
UUID:
uuid:6191d796-3f23-4914-9b75-56f178746c3a
Local pid:
pubs:177367
Source identifiers:
177367
Deposit date:
2012-12-19

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