Journal article icon

Journal article

Erythropoietin does not affect TNF and IL-6 production directly.

Abstract:

The tissue-protective action of erythropoietin (EPO) in animal models is often associated with reduced inflammation. However, there are many contrasting reports of the effect of EPO on the production of inflammatory cytokines induced by lipopolysaccharide (LPS) in vitro, with different papers reporting an inhibition, an upregulation, or a lack of effect. Negative results are likely underestimated by a publication bias. As EPO has anti-inflammatory actions in models associated with tissue inju...

Expand abstract

Actions


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Journal of biological regulators and homeostatic agents
Volume:
27
Issue:
1
Pages:
189-196
Publication date:
2013-01-01
ISSN:
0393-974X
Source identifiers:
470785
Language:
English
Keywords:
Pubs id:
pubs:470785
UUID:
uuid:617e1ce3-e6e4-494d-836f-a6bc1b4aa445
Local pid:
pubs:470785
Deposit date:
2014-07-08

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP