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Stability by multimer resolution of pJHCMW1 is due to the Tn1331 resolvase and not to the Escherichia coli Xer system.

Abstract:

The plasmid pJHCMW1 encodes resistance to several aminoglycosides and beta-lactams and consists of a copy of the transposon Tn1331, a region including the replication functions, and a sequence with homology to ColE1 cer, designated mwr. In this work, the role of this cer-like site in ensuring the stable inheritance of pJHCMW1 by multimer resolution was studied. The Escherichia coli Xer site-specific recombination system acts at sites such as ColE1 cer to resolve plasmid multimers formed by ho...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
Microbiology (Reading, England)
Volume:
146 ( Pt 3)
Issue:
3
Pages:
581-589
Publication date:
2000-03-05
EISSN:
1465-2080
ISSN:
1350-0872
URN:
uuid:6178ef42-d431-4c97-848a-6e30f1c4ab07
Source identifiers:
99849
Local pid:
pubs:99849

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