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A stochastic model for the evolution of metabolic networks with neighbor dependence.

Abstract:

MOTIVATION: Most current research in network evolution focuses on networks that follow a Duplication Attachment model where the network is only allowed to grow. The evolution of metabolic networks, however, is characterized by gain as well as loss of reactions. It would be desirable to have a biologically relevant model of network evolution that could be used to calculate the likelihood of homologous metabolic networks. RESULTS: We describe metabolic network evolution as a discrete space con...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Plant Sciences
Role:
Author
Journal:
Bioinformatics (Oxford, England) More from this journal
Volume:
25
Issue:
12
Pages:
1528-1535
Publication date:
2009-06-01
DOI:
EISSN:
1367-4811
ISSN:
1367-4803
Language:
English
Keywords:
Pubs id:
pubs:34690
UUID:
uuid:6173c829-349a-4163-977f-e3de22af14f6
Local pid:
pubs:34690
Source identifiers:
34690
Deposit date:
2012-12-19

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