- Abstract:
-
Invasive Staphylococcus aureus infection frequently involves bacterial seeding from the bloodstream to other body tissues, a process necessarily involving interactions between circulating bacteria and vascular endothelial cells. Staphylococcus aureus fibronectin-binding protein is central to the invasion of endothelium, fibronectin forming a bridge between bacterial fibronectin-binding proteins and host cell receptors. To dissect further the mechanisms of invasion of endothelial cells by S. a...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1046/j.1462-5822.2001.00157.x
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- Journal:
- Cellular microbiology
- Volume:
- 3
- Issue:
- 12
- Pages:
- 839-851
- Publication date:
- 2001-12-05
- DOI:
- EISSN:
-
1462-5822
- ISSN:
-
1462-5814
- URN:
-
uuid:616fe029-d4e7-4453-8de2-4c6013386bd8
- Source identifiers:
-
23493
- Local pid:
- pubs:23493
- Copyright date:
- 2001
Journal article
Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells.
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