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Sweet taste and nutrient value subdivide rewarding dopaminergic neurons in Drosophila.

Abstract:

Dopaminergic neurons provide reward learning signals in mammals and insects. Recent work in Drosophila has demonstrated that water-reinforcing dopaminergic neurons are different to those for nutritious sugars. Here, we tested whether the sweet taste and nutrient properties of sugar reinforcement further subdivide the fly reward system. We found that dopaminergic neurons expressing the OAMB octopamine receptor specifically convey the short-term reinforcing effects of sweet taste. These dopami...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
Publisher:
Cell Press
Journal:
Current Biology More from this journal
Volume:
25
Issue:
6
Pages:
751-758
Publication date:
2015-02-26
Acceptance date:
2015-01-15
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
Language:
English
Keywords:
Pubs id:
pubs:508670
UUID:
uuid:6167b626-32b0-4eca-ac1a-180b09c9b092
Local pid:
pubs:508670
Source identifiers:
508670
Deposit date:
2016-07-13

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