Cholesterol, diastolic blood pressure, and stroke: 13,000 strokes in 450,000 people in 45 prospective cohorts. Prospective studies collaboration.

Journal article

Individual studies of stroke have not clearly answered two questions: on the relation, if any, between total blood cholesterol and stroke; and on how the strength of the relation between diastolic blood pressure and stroke varies with age. The associations of blood cholesterol and diastolic blood pressure with subsequent stroke rates were investigated by review of 45 prospective observational cohorts involving 450,000 individuals with 5-30 years of follow-up (mean 16 years, total 7.3 million ...

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Authors: Qizilbash, N; Lewington, S; Duffy, S; Peto, R; Smith, T

• Publication status: Published
• Journal: Lancet (London, England)
• Volume: 346
• Issue: 8991-8992
• Pages: 1647-1653
• Publication date: 1995-12-01
• DOI: 10.1016/S0140-6736(95)92836-7
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English
• Keywords: Coronary Disease; Humans; Blood Pressure; Middle Aged; Aged; Risk Factors; Female; Asian Continental Ancestry Group; Male; Age Factors; Prospective Studies; Cohort Studies; Cholesterol; Cerebrovascular Disorders