Journal article
Spectator no more, the role of the membrane in regulating ion channel function
- Abstract:
-
A pressure gradient across a curved lipid bilayer leads to a lateral force within the bilayer. Following ground breaking work on eukaryotic ion channels, it is now known that many proteins sense this change in the lateral tension and alter their functions in response. It has been proposed that responding to pressure differentials may be one of the oldest signaling mechanisms in biology. The most well characterized mechanosensing ion channels are the bacterial ones which open when the pressure...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Chinese National Thousand Talents Program
More from this funder
Funding agency for:
Naismith, J
Grant:
WT100209MA
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Current Opinion in Structural Biology Journal website
- Volume:
- 45
- Pages:
- 56-66
- Publication date:
- 2016-12-07
- DOI:
- EISSN:
-
1879-033X
- ISSN:
-
0959-440X
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:699008
- UUID:
-
uuid:6149b5d4-aea2-4ae6-a71d-5802ed9d0c46
- Local pid:
- pubs:699008
- Source identifiers:
-
699008
- Deposit date:
- 2017-07-24
Terms of use
- Copyright holder:
- © 2016 Elsevier Ltd All rights reserved
- Copyright date:
- 2016
- Notes:
- This is the author accepted manuscript following peer review version of the article. The final version is available online from Elsevier at: 10.1016/j.sbi.2016.10.017
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record