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Clinical features which predict neuronal surface autoantibodies in new-onset focal epilepsy: implications for immunotherapies

Abstract:

Objective To generate a score which clinically identifies surface-directed autoantibodies in adults with new-onset focal epilepsy, and evaluate the value of immunotherapy in this clinical setting.

Methods Prospective clinical and autoantibody evaluations in a cohort of 219 consecutive patients with new-onset focal epilepsy.

Results 10.5% (23/219) of people with new-onset focal epilepsy had detectable serum autoantibodies to...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/jnnp-2020-325011

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
ORCID:
0000-0001-8385-6346
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Publisher:
BMJ Publishing Group Publisher's website
Journal:
Journal of Neurology, Neurosurgery and Psychiatry Journal website
Volume:
92
Issue:
3
Pages:
291-294
Publication date:
2020-11-20
Acceptance date:
2020-10-08
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
Language:
English
Keywords:
Pubs id:
1146624
Local pid:
pubs:1146624
Deposit date:
2020-11-24

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