Journal article
Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial
- Abstract:
-
Background
Doxycycline is often used for treating COVID-19 respiratory symptoms in the community despite an absence of evidence from clinical trials to support its use. We aimed to assess the efficacy of doxycycline to treat suspected COVID-19 in the community among people at high risk of adverse outcomes.Methods
We did a national, open-label, multi-arm, adaptive platform randomised trial of interventions against COVID-19 in older people (PRINC... Expand abstract
- Publication status:
- In press
- Peer review status:
- Peer reviewed
Actions
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet Respiratory Medicine Journal website
- Volume:
- 9
- Issue:
- 9
- Pages:
- 1010-1020
- Publication date:
- 2021-07-27
- Acceptance date:
- 2021-06-15
- DOI:
- ISSN:
-
2213-2600
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1187845
- Local pid:
- pubs:1187845
- Deposit date:
- 2021-07-28
Terms of use
- Copyright holder:
- Elsevier Ltd.
- Copyright date:
- 2021
- Rights statement:
- © 2021 Elsevier Ltd. All rights reserved.
- Notes:
- This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/S2213-2600(21)00310-6
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