Out of Africa: a molecular perspective on the introduction of yellow fever virus into the Americas.
Yellow fever virus (YFV) remains the cause of severe morbidity and mortality in South America and Africa. To determine the evolutionary history of this important reemerging pathogen, we performed a phylogenetic analysis of the largest YFV data set compiled to date, representing the prM/E gene region from 133 viral isolates sampled from 22 countries over a period of 76 years. We estimate that the currently circulating strains of YFV arose in Africa within the last 1,500 years and emerged in th...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
(Version of record, pdf, 550.9KB)
- Publisher copy:
- Local pid:
- Deposit date:
- Copyright date:
- This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
- CC Public Domain Dedication (CC0)
If you are the owner of this record, you can report an update to it here: Report update to this record