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Out of Africa: a molecular perspective on the introduction of yellow fever virus into the Americas.

Abstract:

Yellow fever virus (YFV) remains the cause of severe morbidity and mortality in South America and Africa. To determine the evolutionary history of this important reemerging pathogen, we performed a phylogenetic analysis of the largest YFV data set compiled to date, representing the prM/E gene region from 133 viral isolates sampled from 22 countries over a period of 76 years. We estimate that the currently circulating strains of YFV arose in Africa within the last 1,500 years and emerged in th...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Files:
Publisher copy:
10.1371/journal.ppat.0030075

Authors


Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
3
Issue:
5
Pages:
e75
Publication date:
2007-05-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:613bb23a-dbdf-4fb1-9a97-344a9a50016f
Source identifiers:
195598
Local pid:
pubs:195598

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