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Journal article

Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm.

Abstract:

Little is known of the first transcriptional events that regulate neural fate in response to extracellular signals such as Bmps and Fgfs. Sox3 is one of the earliest transcription factors to be expressed in the developing CNS and has been shown to be regulated by these signalling pathways. We have used both gain- and loss-of-function experiments in zebrafish to elucidate the role of Sox3 in determining neural fate. Ectopic Sox3 caused induction of neural tissue from a very early stage of cell...

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Publication status:
Published

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Publisher copy:
10.1016/j.ydbio.2008.05.542

Authors


Tripathi, VB More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, RDM Clinical Laboratory Sciences
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Journal:
Developmental biology
Volume:
320
Issue:
1
Pages:
289-301
Publication date:
2008-08-05
DOI:
EISSN:
1095-564X
ISSN:
0012-1606
URN:
uuid:61387651-97fa-4b4e-8621-4093a5d39e36
Source identifiers:
106964
Local pid:
pubs:106964

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