Journal article
Sox3 regulates both neural fate and differentiation in the zebrafish ectoderm.
- Abstract:
-
Little is known of the first transcriptional events that regulate neural fate in response to extracellular signals such as Bmps and Fgfs. Sox3 is one of the earliest transcription factors to be expressed in the developing CNS and has been shown to be regulated by these signalling pathways. We have used both gain- and loss-of-function experiments in zebrafish to elucidate the role of Sox3 in determining neural fate. Ectopic Sox3 caused induction of neural tissue from a very early stage of cell...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.ydbio.2008.05.542
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Authors
Bibliographic Details
- Journal:
- Developmental biology
- Volume:
- 320
- Issue:
- 1
- Pages:
- 289-301
- Publication date:
- 2008-08-05
- DOI:
- EISSN:
-
1095-564X
- ISSN:
-
0012-1606
- URN:
-
uuid:61387651-97fa-4b4e-8621-4093a5d39e36
- Source identifiers:
-
106964
- Local pid:
- pubs:106964
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2008
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