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CD44 involvement in experimental collagen-induced arthritis (CIA).

Abstract:

CD44 is a pro-inflammatory cell surface molecule that supports cell migration and cell lodgment in target organs. Therefore, CD44 targeting with specific monoclonal antibodies (mAbs) should be useful for the inhibition of collagen-induced arthritis (CIA) as well as other autoimmune diseases that are dependent on inflammatory cells. In the present paper, we confirm and expand previous reports showing the anti-arthritogenic effect of anti-CD44 mAbs directed against constant epitopes of the CD44...

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Publication status:
Published

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Publisher copy:
10.1006/jaut.1999.0294

Authors


Nedvetzki, S More by this author
Walmsley, M More by this author
Williams, RO More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
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Journal:
Journal of autoimmunity
Volume:
13
Issue:
1
Pages:
39-47
Publication date:
1999-08-05
DOI:
EISSN:
1095-9157
ISSN:
0896-8411
URN:
uuid:6136ddf8-4593-4357-838f-bffcea1f7be0
Source identifiers:
481953
Local pid:
pubs:481953

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