Journal article
Predicting the survival rate of mouse embryonic stem cells cryopreserved in alginate beads.
- Abstract:
-
Stem cell cryopreservation in three-dimensional (3D) scaffolds may offer better protection to cells leading to higher survival rates. However, it introduces heterogeneity in cryoprotective agent (CPA) concentrations, durations of exposure to CPA, and freezing and thawing rate within constructs. This paper applies a mathematical model which couples the mass transport of dimethyl sulphoxide (DMSO) in a cell-seeded spherical construct and cell membrane transport into mouse embryonic stem cells (...
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- Publication status:
- Published
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- Publisher copy:
- 10.1177/0954411911418568
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Bibliographic Details
- Journal:
- Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
- Volume:
- 225
- Issue:
- 11
- Pages:
- 1092-1107
- Publication date:
- 2011-11-01
- DOI:
- EISSN:
-
2041-3033
- ISSN:
-
0954-4119
- Source identifiers:
-
199007
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:199007
- UUID:
-
uuid:612fc986-7f3e-4cad-960c-ef190ebc369a
- Local pid:
- pubs:199007
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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