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Association studies of the 5-HT2A T102C and the 5-HT2C Cys23Ser receptor gene polymorphisms and suicidal behaviour

Abstract:

Disruption of the serotonergic system is suggested to be involved in suicidal behaviour and depression. Results from polymorphism studies have been equivocal in their appraisal of a genetic contribution to this involvement. In the current investigation, the frequencies of the 5-HT2A receptor (T102C) and 5-HT2C receptor (Cys23Ser) polymorphisms were examined in a well-characterised sample of deliberate self-harm (DSH) patients and in healthy controls. DSH patients (n= 144) were recruited from ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
Journal:
AMERICAN JOURNAL OF MEDICAL GENETICS More from this journal
Volume:
105
Issue:
7
Pages:
619-620
Publication date:
2001-10-08
EISSN:
1552-485X
ISSN:
0148-7299
Language:
English
Pubs id:
pubs:98207
UUID:
uuid:612f9c14-cfd6-4d96-be01-1f90e2476636
Local pid:
pubs:98207
Source identifiers:
98207
Deposit date:
2012-12-19

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