Journal article icon

Journal article

Limiting dilution analysis of proliferative responses in human lymphocyte populations defined by the monoclonal antibody UCHL1: implications for differential CD45 expression in T cell memory formation.

Abstract:

Using limiting dilution analysis, we investigated proliferative responses of UCHL1+ and UCHL1- T cell populations to compare the precursor cell frequencies following recall and alloantigen stimulation, and the complexity of cellular interactions within UCHL1+ and UCHL1- populations. We find high frequencies of recall antigen responses among UCHL1+, but not UCHL1- T cells. In contrast, both populations contain similar frequencies of alloantigen responsive cells. Our results are consistent with...

Expand abstract

Actions


Access Document


Publisher copy:
10.1002/eji.1830181102

Authors


Merkenschlager, M More by this author
Edwards, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Journal:
European journal of immunology
Volume:
18
Issue:
11
Pages:
1653-1661
Publication date:
1988-11-05
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
URN:
uuid:612e3dc8-7f7f-44f0-851a-0a729e594321
Source identifiers:
35281
Local pid:
pubs:35281

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP