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Journal article

Integrated bioinformatic analyses and immune characterization of new Neisseria gonorrhoeae vaccine antigens expressed during natural mucosal infection

Abstract:

There is an increasingly severe trend of antibiotic-resistant Neisseria gonorrhoeae strains worldwide and new therapeutic strategies are needed against this sexually-transmitted pathogen. Despite the urgency, progress towards a gonococcal vaccine has been slowed by a scarcity of suitable antigens, lack of correlates of protection in humans and limited animal models of infection. N. gonorrhoeae gene expression levels in the natural human host does not reflect expression in vitro, further compl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/vaccines7040153

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
ORCID:
0000-0002-1623-0295
Publisher:
MDPI Publisher's website
Journal:
Vaccines Journal website
Volume:
7
Issue:
4
Pages:
153
Publication date:
2019-10-17
Acceptance date:
2019-10-14
DOI:
ISSN:
2076-393X
Language:
English
Keywords:
Pubs id:
pubs:1063512
UUID:
uuid:612d1cb2-0f4e-4bee-84cd-b067fb292887
Local pid:
pubs:1063512
Source identifiers:
1063512
Deposit date:
2019-10-18

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