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Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine.

Abstract:

Recent research has demonstrated that all body fluids assessed contain substantial amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by phospholipid membranes containing different membrane microdomains such as lipid rafts and caveolae. The most prominent representatives of these so-called extracellular vesicles (EVs) are nanosized exosomes (70-150 nm), which are derivatives of the endosomal system, and microvesicles (100-1000 nm), which are produced by outward ...

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Publication status:
Published

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Publisher copy:
10.1021/acsnano.5b08015

Authors


O'Driscoll, L More by this author
Borras, FE More by this author
Camussi, G More by this author
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Journal:
ACS nano
Volume:
10
Issue:
4
Pages:
3886-3899
Publication date:
2016-04-05
DOI:
EISSN:
1936-086X
ISSN:
1936-0851
URN:
uuid:61069f5a-d945-410c-a7bc-ce427f82cfae
Source identifiers:
611783
Local pid:
pubs:611783
Language:
English

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