Genetically modified mice lacking the L-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptor subunit, GluR-A (GluR1), and deficient in hippocampal CA3-CA1 long-term potentiation (LTP), were assessed on a novel, hippocampal-dependent spatial reference memory, paddling pool escape task. The mice were required to use the extramaze cues around the laboratory to find a hidden escape tube that was in a constant location at one of 12 possible positions around the perimeter of the pad...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Spatial reference memory in GluR-A-deficient mice using a novel hippocampal-dependent paddling pool escape task.
If you are the owner of this record, you can report an update to it here: Report update to this record