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Journal article

Vitamin D receptor binding, chromatin states and association with multiple sclerosis.

Abstract:

Both genetic and environmental factors contribute to the aetiology of multiple sclerosis (MS). More than 50 genomic regions have been associated with MS susceptibility and vitamin D status also influences the risk of this complex disease. However, how these factors interact in disease causation is unclear. We aimed to investigate the relationship between vitamin D receptor (VDR) binding in lymphoblastoid cell lines (LCLs), chromatin states in LCLs and MS-associated genomic regions. Using the ...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/dds189

Authors


Disanto, G More by this author
Sandve, GK More by this author
Berlanga-Taylor, AJ More by this author
Ragnedda, G More by this author
Morahan, JM More by this author
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Journal:
Human molecular genetics
Volume:
21
Issue:
16
Pages:
3575-3586
Publication date:
2012-08-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:60ee1609-b9aa-4940-80af-a1b98a3ad7eb
Source identifiers:
332775
Local pid:
pubs:332775

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