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Thesis

Primary intestinal epithelial cell response to Helicobacter hepaticus in an ex vivo setting

Abstract:

Epithelial cells lining the intestinal mucosa play a critical role in mucosal immune homeostasis. The inability to culture primary intestinal epithelial cells (IEC) in vitro, limited their use in ex vivo IEC functional studies. Recently, a method for developing primary intestinal crypt-like 3D structures termed organoids was described. The aim of this project was to establish 2D primary IEC monolayers that could be used to dissect the innate immune response of primar...

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Division:
MSD
Department:
Pathology Dunn School
Role:
Author

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Role:
Supervisor
Saudi Arabian Ministry of Higher Education More from this funder
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
UUID:
uuid:60dbb087-7cbc-4c4b-bc15-7cce3a3389bd
Deposit date:
2017-02-20

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