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Thesis

Primary intestinal epithelial cell response to Helicobacter hepaticus in an ex vivo setting

Abstract:

Epithelial cells lining the intestinal mucosa play a critical role in mucosal immune homeostasis. The inability to culture primary intestinal epithelial cells (IEC) in vitro, limited their use in ex vivo IEC functional studies. Recently, a method for developing primary intestinal crypt-like 3D structures termed organoids was described. The aim of this project was to establish 2D primary IEC monolayers that could be used to dissect the innate immune response of primar...

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Sarah Alrawaf More by this author

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Role:
Supervisor
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford

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