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Journal article

Membrane proteins bind lipids selectively to modulate their structure and function.

Abstract:

Previous studies have established that the folding, structure and function of membrane proteins are influenced by their lipid environments and that lipids can bind to specific sites, for example, in potassium channels. Fundamental questions remain however regarding the extent of membrane protein selectivity towards lipids. Here we report a mass spectrometry approach designed to determine the selectivity of lipid binding to membrane protein complexes. We investigate the mechanosensitive channe...

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Publication status:
Published

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Publisher copy:
10.1038/nature13419

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Journal:
Nature
Volume:
510
Issue:
7503
Pages:
172-175
Publication date:
2014-06-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:60d72edd-81d1-45e6-bcaa-6709acf67dd6
Source identifiers:
469443
Local pid:
pubs:469443

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