Journal article icon

Journal article

Lessons for tuberculosis vaccines from respiratory virus infection.

Abstract:

There is a worldwide epidemic of increasingly drug-resistant TB. Bacillus Calmette-Guérin vaccination provides partial protection against disseminated disease in infants but poor protection against later pulmonary TB. Cell-mediated protection against respiratory virus infections requires the presence of T cells in lung tissues, and the most effective prime-boost immunizations for Mycobacterium tuberculosis also induce lung-resident lymphocytes. These observations need to be taken into account...

Expand abstract

Actions


Access Document


Publisher copy:
10.1586/14760584.7.8.1165

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Tchilian, EZ More by this author
Journal:
Expert review of vaccines
Volume:
7
Issue:
8
Pages:
1165-1172
Publication date:
2008-10-05
DOI:
EISSN:
1744-8395
ISSN:
1476-0584
URN:
uuid:60cffaa9-b0e6-4826-abe6-e1105204e7ba
Source identifiers:
34417
Local pid:
pubs:34417

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP