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GLYCOSIDASE INHIBITION BY PLANT ALKALOIDS WHICH ARE STRUCTURAL ANALOGS OF MONOSACCHARIDES

Abstract:

]The inhibitory activities of three plant alkaloids, deoxynojirimycin, 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine and 1,5 dideoxy-1,5-imino-D-mannitol towards glycosidases from several sources have been compared. These are structural analogues of D-glucose, D-fructose and D-mannose respectively. The occurrence of 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine in Lonchocarpus sericeus seed is confirmed and has been shown to be responsible for the glucosidase inhibition wrongly attributed to 1,...

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Publication status:
Published

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Authors


FELLOWS, L More by this author
Journal:
PHYTOCHEMISTRY
Volume:
24
Issue:
9
Pages:
1953-1955
Publication date:
1985
DOI:
ISSN:
0031-9422
URN:
uuid:60bb5606-6623-4d6d-9088-0b2a9c04a2aa
Source identifiers:
42486
Local pid:
pubs:42486

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