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Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations.

Abstract:

Brain natriuretic peptide (BNP/NPPB) is a member of the natriuretic family involved in the regulation of blood pressure and blood volume as well as lipolysis control in human fat cells. Thus BNP may play a role in energy metabolism and metabolic diseases. We therefore assessed the association between the BNP promoter T-381C polymorphism and risk of type 2 diabetes and metabolic and BNP expression traits in several population samples. In French population-based samples (n = 3216), we found tha...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddm084

Authors


Meirhaeghe, A More by this author
Sandhu, MS More by this author
McCarthy, MI More by this author
de Groote, P More by this author
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Journal:
Human molecular genetics
Volume:
16
Issue:
11
Pages:
1343-1350
Publication date:
2007-06-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:609f1670-a468-46d9-a7e3-8ef9b3cfb9c7
Source identifiers:
28794
Local pid:
pubs:28794

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