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New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

Abstract:

Birth weight within the normal range is associated with a variety of adult-onset diseases, but the mechanisms behind these associations are poorly understood. Previous genome-wide association studies of birth weight identified a variant in the ADCY5 gene associated both with birth weight and type 2 diabetes and a second variant, near CCNL1, with no obvious link to adult traits. In an expanded genome-wide association meta-anal...

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Publication status:
Published

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Publisher copy:
10.1038/ng.2477

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Journal:
Nature genetics
Volume:
45
Issue:
1
Pages:
76-82
Publication date:
2013-01-01
DOI:
EISSN:
1546-1718
ISSN:
1061-4036
Source identifiers:
365460

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